Purified Anti-Human CD29 Antibody[TS2/16.2.1], Functional Grade (E-AB-F10490)
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For research use only.
| Alternate Names | MSK, MDF, ITB, ITGB, Integrin β, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB, Integrin beta 1, ITGB1, Integrin β1, Fibronectin receptor subunit beta, Integrin beta-1, ITB1, VLA-4 subunit beta, integrin &, beta-1-1, gpIIa, antigen CD29 includes MDF2, beta 1 (fibronectin receptor, beta polypeptide, beta1 integrin, Glycoprotein IIa, GP IIa, Integrin, Integrin subunit beta 1, integrin VLA-4 beta subunit, MSK12), OTTHUMP00000019420, Very late activation protein, VLA BETA, VLAbeta |
| Clone | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells);Activ Reported in the literaturee |
| Background | CD29 is a 130 kD single chain type I glycoprotein also known as integrin β1, VLA-β chain, or gpIIa. It is broadly expressed on a majority of hematopoietic and non-hematopoietic cells, including leukocytes (although at low level on granulocytes), platelets, fibroblasts, endothelial cells, epithelial cells, and mast cells. CD29 is a member of the integrin family. It is non-covalently associated with integrin α1-α6 chains to form VLA-1 to VLA-6 molecules, respectively. Integrins, which include CD29, bind to several cell surface (e.g. VCAM-1, MadCAM-1) and extracellular matrix molecules. CD29 acts as a fibronectin receptor and is involved in a variety of cell-cell and cell-matrix interactions. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
| Immunogen | Recombinant Human CD29 protein |
| Abbre | CD29 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Isotype Control | Purified Mouse IgG1, κ Isotype Control[MOPC-21], Functional Grade |
| Applications |
FCM;Activ
|
| Research Areas | Signal Transduction;Cancer;Metabolism;Neuroscience;Microbiology;Stem Cells;Developmental Biology |
| Concentration |
≥ 1 mg/mL
|
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
| Application References | Sanchez-Aparicio P, et al. J Cell Biol. 1994 Aug;126(2):271. |
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